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Raben D, Helfrich BA, Chan D, Johnson G, Bunn PA ZD1839, a selective epidermal growth factor receptor tyrosine kinase inhibitor, alone and in combination with radiation and chemotherapy as a new therapeutic strategy in non-small cell lung cancer.

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On the basis of the findings in the melanoma models and given that EGFR is one of the most commonly mutated oncogenes in NSCLC (), we analyzed the immune microenvironment and a set of immunosuppressive pathways in EGFR-driven mouse lung tumors.

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Another trial that offers a great opportunity for patients to enter adjuvant trials with new investigational drugs is the ALCHEMIST (A151216) trial.

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